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1

Fracture healing: mechanisms and interventions

Einhorn, Thomas A., Gerstenfeld, Louis C.

Journal:

Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology)

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

2

Diabetes Causes Decreased Osteoclastogenesis, Reduced Bone Formation, and Enhanced Apoptosis of Osteoblastic Cells in Bacteria Stimulated Bone Loss

He, Hongbing, Liu, Rongkun, Desta, Tesfahun, Leone, Cataldo, Gerstenfeld, Louis C., Graves, Dana T.

Journal:

Year:

2004

Language:

english

File:

PDF, 238 KB

english, 2004

3

Device for the application of a dynamic biaxially uniform and isotropic strain to a flexible cell culture membrane

Jonathan L. Schaffer, Michael Rizen, Gilbert J. L'Italien, Aziz Benbrahim, Joseph Megerman, Louis C. Gerstenfeld, Dr. Martha L. Gray

Journal:

Journal of Orthopaedic Research

Year:

1994

Language:

english

File:

PDF, 1.01 MB

english, 1994

4

Mechanism of action and morphologic changes in the alveolar bone in response to selective alveolar decortication–facilitated tooth movement

S. Susan Baloul, Louis C. Gerstenfeld, Elise F. Morgan, Roberto S. Carvalho, Thomas E. Van Dyke, Alpdogan Kantarci

Journal:

American Journal of Orthodontics and Dentofacial Orthopedics

Year:

2011

Language:

english

File:

PDF, 1.78 MB

english, 2011

5

Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways

Mani Alikhani, Zoubin Alikhani, Coy Boyd, Christine M. MacLellan, Markos Raptis, Rongkun Liu, Nicole Pischon, Philip C. Trackman, Louis Gerstenfeld, Dana T. Graves

Journal:

Year:

2007

Language:

english

File:

PDF, 560 KB

english, 2007

6

Effect of protein-hydroxyethylmethacrylate hydrogels on cultured endothelial cells

Barbara Faris, Patricia Mozzicato, Peter J. Mogayzel Jr, Rocco Ferrera, Louis C. Gerstenfeld, Michael Glembourtt, Joseph S. Makarski Jr, Christian C. Haudenschild, Carl Franzblau

Journal:

Experimental Cell Research

Year:

1983

Language:

english

File:

PDF, 6.08 MB

english, 1983

7

Qualitative and Quantitative Differences Between Bone Graft Obtained from the Medullary Canal (with a Reamer/Irrigator/Aspirator) and the Iliac Crest of the Same Patient

Sagi, H. Claude, Young, Megan L., Gerstenfeld, Louis, Einhorn, Thomas A., Tornetta, Paul

Journal:

The Journal of Bone and Joint Surgery (American)

Year:

2012

Language:

english

File:

PDF, 1.80 MB

english, 2012

8

Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs

Louis C Gerstenfeld, Mark Thiede, Karen Seibert, Cindy Mielke, Deborah Phippard, Bohus Svagr, Dennis Cullinane, Thomas A Einhorn

Journal:

Journal of Orthopaedic Research

Year:

2003

Language:

english

File:

PDF, 778 KB

english, 2003

9

Osteopontin in Skeletal Tissue Homeostasis: An Emerging Picture of the Autocrine/Paracrine Functions of the Extracellular Matrix

LOUIS C. Gerstenfeld

Journal:

Journal of Bone and Mineral Research

Year:

1999

Language:

english

File:

PDF, 88 KB

english, 1999

10

Tendon regeneration and scar formation: The concept of scarless healing

Galatz, Leesa M., Gerstenfeld, Louis, Heber-Katz, Ellen, Rodeo, Scott A.

Journal:

Journal of Orthopaedic Research

Year:

2015

Language:

english

File:

PDF, 760 KB

english, 2015

11

Transcriptional regulation restricting bone sialoprotein gene expression to both hypertrophic chondrocytes and osteoblasts

George L. Barnes, Thomas Della Torre, Beatrice Sommer, Marian F. Young, Louis C. Gerstenfeld

Journal:

Journal of Cellular Biochemistry

Year:

2002

Language:

english

File:

PDF, 238 KB

english, 2002

12

Application of Histomorphometric Methods to the Study of Bone Repair

Louis C Gerstenfeld, Thomas J Wronski, Jeffrey O Hollinger, Thomas A Einhorn

Journal:

Journal of Bone and Mineral Research

Year:

2005

Language:

english

File:

PDF, 1.53 MB

english, 2005

13

The Onset and Progression of Osteoblast Differentiation is Functionally Related to Cellular Proliferation

Stein, S. Gary, Lian, B. Jane, Gerstenfeld, G. Louis, Victoria, Shalhoub, Michael, Aronow, Thomas, Owen, Elizabeth, Markose

Journal:

Connective Tissue Research

Year:

1989

Language:

english

File:

PDF, 476 KB

english, 1989

14

Characterization of a cDNA for chicken osteopontin: expression during bone development, osteoblast differentiation, and tissue distribution

Moore, Mark A., Gotoh, Yozo, Rafidi, Kristina, Gerstenfeld, Louis C.

Journal:

Year:

1991

Language:

english

File:

PDF, 2.70 MB

english, 1991

15

Clustering of temporal gene expression data with mixtures of mixed effects models with a penalized likelihood

Lu, Darlene, Tripodis, Yorghos, Gerstenfeld, Louis, Demissie, Serkalem, Wren, Jonathan

Journal:

Year:

2018

Language:

english

File:

PDF, 1.93 MB

english, 2018

16

Gene Expression and Extracellular Matrix Ultrastructure of a Mineralizing Chondrocyte Cell Culture System

Louis C. Gerstenfeld and William J. Landis

Journal:

The Journal of Cell Biology

Year:

1991

Language:

english

File:

PDF, 3.43 MB

english, 1991

17

The hypoxia-inducible factor α pathway couples angiogenesis to osteogenesis during skeletal development

Wang, Ying, Wan, Chao, Deng, Lianfu, Liu, Ximeng, Cao, Xuemei, Gilbert, Shawn R., Bouxsein, Mary L., Faugere, Marie-Claude, Guldberg, Robert E., Gerstenfeld, Louis C., Haase, Volker H., Johnson, Randa

Journal:

Journal of Clinical Investigation

Year:

2007

Language:

english

File:

PDF, 1.19 MB

english, 2007

18

AMPK downregulates ALK2 via increasing the interaction between Smurf1 and Smad6, leading to inhibition of in vitro osteogenic differentiation

Lin, Hui, Ying, Ying, Wang, Yuan-Yuan, Wang, Gang, Jiang, Shan-Shan, Huang, Deiang, Luo, Lingyu, Chen, Ye-Guang, Gerstenfeld, Louis C., Luo, Zhijun

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

19

Structural analysis and characterization of tissue and hormonal responsive expression of the avian bone sialoprotein (BSP) gene

Renji Yang, Louis C. Gerstenfeld

Journal:

Journal of Cellular Biochemistry

Year:

1997

Language:

english

File:

PDF, 271 KB

english, 1997

20

Neuropilin-1 expression in osteogenic cells: Down-regulation during differentiation of osteoblasts into osteocytes

Jay Harper, Louis C. Gerstenfeld, Michael Klagsbrun

Journal:

Journal of Cellular Biochemistry

Year:

2001

Language:

english

File:

PDF, 240 KB

english, 2001

21

Experiments with osteoblasts cultured under hypergravity conditions

Melissa A. Kacena, Paul Todd, Louis C. Gerstenfeld, William J. Landis

Journal:

Microgravity Science and Technology

Year:

2004

Language:

english

File:

PDF, 243 KB

english, 2004

22

Comparison of Effects of the Bisphosphonate Alendronate Versus the RANKL Inhibitor Denosumab on Murine Fracture Healing

Louis C Gerstenfeld, Daniel J Sacks, Megan Pelis, Zachary D Mason, Dana T Graves, Mauricio Barrero, Michael S Ominsky, Paul J Kostenuik, Elise F Morgan, Thomas A Einhorn

Journal:

Journal of Bone and Mineral Research

Year:

2009

Language:

english

File:

PDF, 2.11 MB

english, 2009

23

Identification and characterization of the major chicken bone phosphoprotein : Analysis of its synthesis by cultured embryonic chick osteoblasts

Yozo GOTOH, Louis C. GERSTENFELD, Melvin J. GLIMCHER

Journal:

Year:

1990

Language:

english

File:

PDF, 1.18 MB

english, 1990

24

COX inhibitors and their effects on bone healing

Gerstenfeld, Louis C, Einhorn, Thomas A

Journal:

Expert Opinion on Drug Safety

Year:

2004

Language:

english

File:

PDF, 108 KB

english, 2004

25

Functional role of Runx3 in the regulation of aggrecan expression during cartilage development

Wigner, Nathan A., Soung, Do Y., Einhorn, Thomas A., Drissi, Hicham, Gerstenfeld, Louis C.

Journal:

Journal of Cellular Physiology

Year:

2013

Language:

english

File:

PDF, 1012 KB

english, 2013

26

Acute Phosphate Restriction Impairs Bone Formation and Increases Marrow Adipose Tissue in Growing Mice

Ko, Frank C, Martins, Janaina S, Reddy, Pooja, Bragdon, Beth, Hussein, Amira I, Gerstenfeld, Louis C, Demay, Marie B

Journal:

Journal of Bone and Mineral Research

Year:

2016

Language:

english

File:

PDF, 1.58 MB

english, 2016

27

Earliest phases of chondrogenesis are dependent upon angiogenesis during ectopic bone formation in mice

Bragdon, Beth, Lam, Stephanie, Aly, Sherif, Femia, Alexandra, Clark, Abigail, Hussein, Amira, Morgan, Elise F., Gerstenfeld, Louis C.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.90 MB

english, 2017

28

Mechanical stimulation alters tissue differentiation and molecular expression during bone healing

Kristy T. Salisbury Palomares, Ryan E. Gleason, Zachary D. Mason, Dennis M. Cullinane, Thomas A. Einhorn, Louis C. Gerstenfeld, Elise F. Morgan

Journal:

Journal of Orthopaedic Research

Year:

2009

Language:

english

File:

PDF, 579 KB

english, 2009

29

Micro-computed tomography assessment of fracture healing: Relationships among callus structure, composition, and mechanical function

Elise F. Morgan, Zachary D. Mason, Karen B. Chien, Anthony J. Pfeiffer, George L. Barnes, Thomas A. Einhorn, Louis C. Gerstenfeld

Journal:

Year:

2009

Language:

english

File:

PDF, 1.19 MB

english, 2009

30

Comparison of two phosphoproteins in chicken bone and their similarities to the mammalian bone proteins, osteopontin and bone sialoprotein II

Yozo Gotoh, Michael D. Pierschbacher, John J. Grzesiak, Louis Gerstenfeld, Melvin J. Glimcher

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 979 KB

english, 1990

31

Healing of Segmental Bone Defects by Direct Percutaneous Gene Delivery: Effect of Vector Dose

Betz, Volker M., Betz, Oliver B., Glatt, Vaida, Gerstenfeld, Louis C., Einhorn, Thomas A., Bouxsein, Mary L., Vrahas, Mark S., Evans, Christopher H.

Journal:

Human Gene Therapy

Year:

2007

Language:

english

File:

PDF, 608 KB

english, 2007

32

Tumor necrosis factor α activation of the apoptotic cascade in murine articular chondrocytes is associated with the induction of metalloproteinases and specific pro-resorptive factors

Tae-Joon Cho, Wolfgang Lehmann, Cory Edgar, Cameron Sadeghi, Andrew Hou, Thomas A. Einhorn, Louis C. Gerstenfeld

Journal:

Arthritis & Rheumatism

Year:

2003

Language:

english

File:

PDF, 350 KB

english, 2003

33

Identification of the In Vivo Phosphorylated Sites of Secreted Osteopontin from Cultured Chicken Osteoblasts

ERDJAN SALIH, SAMY ASHKAR, LOUIS C. GERSTENFELD, MELVIN J. GLIMCHER

Journal:

Annals of the New York Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 170 KB

english, 1995

34

Cytokines and fracture healing

Cho, Tae-Joon, Gerstenfeld, Louis C., Barnes, George L., Einhorn, Thomas A.

Journal:

Current Opinion in Orthopaedics

Year:

2001

Language:

english

File:

PDF, 79 KB

english, 2001

35

Experimental Use of Fibrin Glue to Induce Site-Directed Osteogenesis from Cultured Periosteal Cells

Isogai, Noritaka, Landis, William J., Mori, Ryuji, Gotoh, Yozo, Gerstenfeld, Louis C., Upton, Joseph, Vacanti, Joseph P.

Journal:

Plastic & Reconstructive Surgery

Year:

2000

Language:

english

File:

PDF, 893 KB

english, 2000

36

Transcriptional profiling and biochemical analysis of mechanically induced cartilaginous tissues in a rat model

Kristy T. Salisbury Palomares, Louis C. Gerstenfeld, Nathan A. Wigner, Marc E. Lenburg, Thomas A. Einhorn, Elise F. Morgan

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 260 KB

english, 2010

37

BMP treatment of C3H10T1/2 mesenchymal stem cells induces both chondrogenesis and osteogenesis

Colleen M. Shea, Cory M. Edgar, Thomas A. Einhorn, Louis C. Gerstenfeld

Journal:

Journal of Cellular Biochemistry

Year:

2003

Language:

english

File:

PDF, 546 KB

english, 2003

38

Chemokine expression is upregulated in chondrocytes in diabetic fracture healing

Alblowi, Jazia, Tian, Chen, Siqueira, Michelle F., Kayal, Rayyan A., McKenzie, Erin, Behl, Yugal, Gerstenfeld, Louis, Einhorn, Thomas A., Graves, Dana T.

Journal:

Year:

2013

Language:

english

File:

PDF, 468 KB

english, 2013

39

Mechanical stimulation of bone

Clint Rubin, Louis Gerstenfeld

Journal:

Annals of Biomedical Engineering

Year:

1997

Language:

english

File:

PDF, 149 KB

english, 1997

40

BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing

Tsuji, Kunikazu, Bandyopadhyay, Amitabha, Harfe, Brian D, Cox, Karen, Kakar, Sanjeev, Gerstenfeld, Louis, Einhorn, Thomas, Tabin, Clifford J, Rosen, Vicki

Journal:

Nature Genetics

Year:

2006

Language:

english

File:

PDF, 718 KB

english, 2006

41

Transient Chondrogenic Phase in the Intramembranous Pathway During Normal Skeletal Development

Hyun-Duck Nah, Maurizio Pacifici, Louis C. Gerstenfeld, Sherrill L. Adams, Thorsten Kirsch

Journal:

Journal of Bone and Mineral Research

Year:

2000

Language:

english

File:

PDF, 2.22 MB

english, 2000

42

Expression of differentiated function by mineralizing cultures of chicken osteoblasts

Louis C. Gerstenfeld, Stewart D. Chipman, Julie Glowacki, Jane B. Lian

Journal:

Developmental Biology

Year:

1987

Language:

english

File:

PDF, 10.07 MB

english, 1987

43

Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment

Rayyan A. Kayal, Jazia Alblowi, Erin McKenzie, Nanarao Krothapalli, Lee Silkman, Louis Gerstenfeld, Thomas A. Einhorn, Dana T. Graves

Journal:

Year:

2009

Language:

english

File:

PDF, 899 KB

english, 2009

44

Sex-Linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice

Alsofi, Loai, Daley, Eileen, Hornstra, Ian, Morgan, Elise F., Mason, Zachary D., Acevedo, Jesus F., Word, R. Ann, Gerstenfeld, Louis C., Trackman, Philip C.

Journal:

Calcified Tissue International

Year:

2016

Language:

english

File:

PDF, 6.68 MB

english, 2016

45

Lysyl Oxidase-Like 2 Protects against Progressive and Aging Related Knee Joint Osteoarthritis in Mice

Tashkandi, Mustafa, Ali, Faiza, Alsaqer, Saqer, Alhousami, Thabet, Cano, Amparo, Martin, Alberto, Salvador, Fernando, Portillo, Francisco, C. Gerstenfeld, Louis, Goldring, Mary B., Bais, Manish V.

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 3.76 MB

english, 2019

46

Fracture healing as a post-natal developmental process: Molecular, spatial, and temporal aspects of its regulation

Louis C. Gerstenfeld, Dennis M. Cullinane, George L. Barnes, Dana T. Graves, Thomas A. Einhorn

Journal:

Journal of Cellular Biochemistry

Year:

2003

Language:

english

File:

PDF, 522 KB

english, 2003

47

Diminished Bone Formation During Diabetic Fracture Healing is Related to the Premature Resorption of Cartilage Associated With Increased Osteoclast Activity

Rayyan A Kayal, Dimitris Tsatsas, Megan A Bauer, Brian Allen, Maisa O Al-Sebaei, Sanjeev Kakar, Cataldo W Leone, Elise F Morgan, Louis C Gerstenfeld, Thomas A Einhorn, Dana T Graves

Journal:

Journal of Bone and Mineral Research

Year:

2007

Language:

english

File:

PDF, 3.93 MB

english, 2007

48

Genetic Variation in the Patterns of Skeletal Progenitor Cell Differentiation and Progression During Endochondral Bone Formation Affects the Rate of Fracture Healing

Karl J Jepsen, Christopher Price, Lee J Silkman, Fred H Nicholls, Phillip Nasser, Bin Hu, Nicole Hadi, Michael Alapatt, Stephanie N Stapleton, Sanjeev Kakar, Thomas A Einhorn, Louis C Gerstenfeld

Journal:

Journal of Bone and Mineral Research

Year:

2008

Language:

english

File:

PDF, 5.66 MB

english, 2008

49

Molecular Events that Contribute to Lysyl Oxidase Enzyme Activity and Insoluble Collagen Accumulation in Osteosarcoma Cell Clones

Mehmet I. Uzel, Sarah D. Shih, Howard Gross, Efrat Kessler, Louis C. Gerstenfeld, Philip C. Trackman

Journal:

Journal of Bone and Mineral Research

Year:

2000

Language:

english

File:

PDF, 1.48 MB

english, 2000

50

Skeletal trauma generates systemic BMP2 activation that is temporally related to the mobilization of CD73+ cells

Marsell, Richard, Steen, Brandon, Bais, Manish V., Mortlock, Douglas P., Einhorn, Thomas A., Gerstenfeld, Louis C.

Journal:

Journal of Orthopaedic Research

Year:

2014

Language:

english

File:

PDF, 3.01 MB

english, 2014

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